Submit Manuscript  

Article Details

Sustainable Synthetic Approaches Involving Thiocyanation and Sulfur- Cyanation: An Update

[ Vol. 7 , Issue. 2 ]


Mihaela Gulea* and Morgan Donnard*   Pages 201 - 216 ( 16 )


This review highlights the achievements in the synthesis of organic thiocyanates (OTCs) over the past five years (late 2015 to mid-2019) and is intended as a follow-up on our tutorial review published in Chemical Society Reviews in 2016. The discussion places a special emphasis on sustainable synthetic approaches involving thiocyanation or sulfur-cyanation. The large number of contributions within this short period of time clearly indicates that the chemistry of OTCs provides a growing interest and a rapid evolution.


Organic thiocyanates, thiocyanation, S-cyanation, sustainable synthetic methods, domino reactions, multicomponent reactions, difunctionalization.


Universite de Strasbourg, Laboratoire d’Innovation Therapeutique (LIT), UMR7200, CNRS, Faculte de Pharmacie, 74 Route du Rhin, 67401 Illkirch, Universite de Strasbourg, CNRS, Universite de Haute-Alsace, LIMA – UMR7042, Ecole Europeenne de Chimie, Polymeres et Materiaux (ECPM), 67000 Strasbourg

Graphical Abstract:

Read Full-Text article