Visible Light Assisted Synthesis of 5-Aryl-1,2,4-thiazolidine-3-thiones Under Catalyst-free Condition

Author(s):

Amol Khandebharad*, Swapnil Sarda, Pravin Kulkarni and Brijmohan Agrawal   Pages 326 - 333 ( 8 )

Abstract:

Light energy can be considered as an ideal eco-friendly source of energy for green chemistry. This perspective was used to synthesize 5-aryl-1,2,4-thiazolidine-3-thiones derivative as a quick, efficient and highly improved protocol. The present method developed an energy competent and integrated technique by one-pot condensations of aromatic aldehyde and thiosemicarbazide under the catalyst-free condition in aqueous-alcoholic media. The impact of light on reaction along with mechanical stirring provided a prominent yield of the product. The mild reaction conditions, short reaction time and easy workup procedure, avoidance of heavy metal catalyst and harsh reaction conditions make this protocol greener.

Keywords:

Aromatic aldehyde, thiosemicarbazide, water: ethanol (1:1), visible light, thio-triazole derivatives, green chemistry.

Affiliation:

Department of Chemistry, J.E.S. College, Jalna (MS), Department of Chemistry, J.E.S. College, Jalna (MS), Department of Chemistry, J.E.S. College, Jalna (MS), Department of Chemistry, J.E.S. College, Jalna (MS)

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